Season Two: Uterine Cancers

On The Down Low – Season 2: it’s time to start talking about uterine cancers

After the success of its award-winning first season, On The Down Low – Speaking Up About Gynaecological Cancer returns with a powerful second series, this time shining a spotlight on uterine cancers, including endometrial cancer, the most commonly diagnosed gynaecological cancer in Australia.

Despite rapidly rising rates, uterine cancers remain largely unknown, underfunded, and under-researched. Over the past 20 years, incidence has doubled in Australia and nearly tripled in New Zealand, with diagnoses particularly increasing among women aged 30–50, highlighting an urgent need for awareness, education, and investment.

Hosted again by Alison Dance, this six-part season shares real stories from people with lived experience of uterine cancers, alongside insights from leading ANZGOG experts. Listeners will learn to recognise risk factors and warning signs, understand early diagnosis and treatment options including fertility-sparing approaches, and gain perspective on current research, survivorship, and advocacy. Every episode emphasises the importance of speaking up, asking questions, and exploring options to improve outcomes for women.

Season 2 was produced by ANZGOG, with the generous support of Eisai and GSK.

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Available episodes


Season 2, Episode 1 (S2.E1): Prevention, Risk and Early Diagnosis (Including Genetic Factors)

Wednesday 17 September 2025

The body often whispers before it screams — and recognising those early whispers can save lives. In this episode, we explore the importance of listening to symptoms like abnormal bleeding, and the role of risk factors such as obesity, hormones, lifestyle, and genetic predispositions including Lynch Syndrome. Through lived experience stories from Carly and Ruth, and expert insights from Professor Alison Brand AM, we uncover how prevention, risk assessment, and early diagnosis can change the future of gynaecological cancers.


Season 2, Episode 2 (S2.E2): Surgery and Fertility Sparing / Considerations

Wednesday 24 September 2025

A gynaecological cancer diagnosis shouldn’t take away the right to plan your future. This episode delves into surgical options and fertility considerations, highlighting minimally invasive versus open surgery, fertility-sparing treatments, hormonal therapy pathways, and the emotional and reproductive impacts of surgical decisions.

Through lived experience from Mina and expert guidance from Professor Alison Brand AM, we explore how surgical innovations can support both health and future family planning. Ask questions, explore your options, and take an active role in your care.


Season 2, Episode 3 (S2.E3): The Research, Treatment and Epidemiology

Wednesday 1 October 2025

The science is advancing — but only if the system keeps pace. This episode explores emerging treatments for gynaecological cancer, including immunotherapy and targeted drugs, and examines disparities in access to clinical trials and advanced care. We also review epidemiological trends and the rising incidence of these cancers.

Through lived experience stories from Alex and Rod and expert insights from Professor Alison Brand AM, we highlight the importance of supporting research and advocating for equitable access, ensuring science translates into real-world impact.


Season 2, Episode 4 (S2.E4): Uterine Cancer (Challenges of Rare Cancer)

Wednesday 8 October 2025

Rare doesn’t just mean statistics — it’s a lived experience of uncertainty and invisibility. This episode explores rare uterine cancer subtypes, the challenges in treating them, and the gaps in research, clinical trials, and funding. We also examine the emotional impact of misdiagnosis, delays, and being overlooked.

Featuring lived experience stories from Ali and Jane, alongside expert insights from Professor Alison Brand AM, this episode highlights the critical need for translational research. Even if it’s rare, your voice matters — speak, share, and advocate for attention.


Season 2, Episode 5 (S2.E5): Survivorship, Surveillance and Rehabilitation, Long-Term Side Effects

Wednesday 15 October 2025

Survival is only half the story — living well after cancer is its own journey. This episode explores the long-term physical side effects of gynaecological cancer, including menopause and fatigue, and the emotional and identity recovery that follows treatment. We also cover exercise, rehabilitation, and tailored survivorship support.

Featuring lived experience stories from Jane (New Zealand) and Ann (Australia), alongside expert insights from Professor Alison Brand AM, this episode highlights that survivorship deserves as much care as treatment. You’re not alone — support is available every step of the way.


Season 2, Episode 6 (S2.E6): Advocacy: What Women Need to Know (From a Patient and Clinician Perspective)

Wednesday 22 October 2025

Uterine cancers are common, serious, and still too quiet — it’s time to speak louder. This episode examines public invisibility and stigma, what all women need to know about symptoms and self-advocacy, and the power of storytelling to influence policy, funding, and culture.

Featuring lived experience voices from Shirley, Mina, Ann, Carley, Alex, Ali, Ruth and Jane, alongside expert insights from Professor Alison Brand AM, this episode amplifies patient voices and highlights the importance of advocacy. Let’s break the silence — share this, fund this, and help drive change.

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